Abstract: Recently, Bendersky and Thompson introduced a spectral sequence which, for many spaces X, converges to the v1-periodic homotopy groups of X. It is proved that the E2-term of this spectral sequence is given by Ext in the category of stable p-adic Adams modules of PK^1(X;Zphat)/im(psi^p). We compute this spectral sequence when p=2 and X is the exceptional Lie group F4, yielding as a new result the v1-periodic homotopy groups of F4. Some new general results about convergence of this spectral sequence are also proved.